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Role of the dynamic tumor microenvironment in controversies regarding immune checkpoint inhibitors for the treatment of non-small cell lung cancer (NSCLC) with EGFR mutations

Immunotherapy has been incorporated into the first- and second-line treatment strategies for non-small cell lung cancer (NSCLC), profoundly ushering in a new treatment landscape. However, both adaptive signaling and oncogenic (epidermal growth factor receptor (EGFR)-driven) signaling may induce PD-L...

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Detalhes bibliográficos
Publicado no:Mol Cancer
Main Authors: Lin, Anqi, Wei, Ting, Meng, Hui, Luo, Peng, Zhang, Jian
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6745797/
https://ncbi.nlm.nih.gov/pubmed/31526368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-019-1062-7
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