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ATM Mutations Benefit Bladder Cancer Patients Treated With Immune Checkpoint Inhibitors by Acting on the Tumor Immune Microenvironment

Immune checkpoint inhibitors (ICIs) have shown promising results in bladder cancer (BC). However, only some patients respond to ICIs. DNA repair defects (DDR) play an important role in the therapeutic response of bladder cancer. Therefore, we aimed to elucidate the association between ICIs in bladde...

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Bibliografske podrobnosti
izdano v:Front Genet
Main Authors: Yi, Ruibin, Lin, Anqi, Cao, Manming, Xu, Abai, Luo, Peng, Zhang, Jian
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7456912/
https://ncbi.nlm.nih.gov/pubmed/32922441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2020.00933
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