Validation of a clinical-genetics score to predict hemorrhagic transformations after rtPA

OBJECTIVE: To validate the Genot-PA score, a clinical-genetic logistic regression score that stratifies the thrombolytic therapy safety, in a new cohort of patients with stroke. METHODS: We enrolled 1,482 recombinant tissue plasminogen activator (rtPA)-treated patients with stroke in Spain and Finla...

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Publicado en:Neurology
Autores principales: Carrera, Caty, Cullell, Natalia, Torres-Águila, Nuria, Muiño, Elena, Bustamante, Alejandro, Dávalos, Antonio, López-Cancio, Elena, Ribó, Marc, Molina, Carlos A., Giralt-Steinhauer, Eva, Soriano-Tárraga, Carolina, Mola-Caminal, Marina, Jiménez-Conde, Jordi, Roquer, Jaume, Vives-Bauza, Cristófol, Navarro, Rosa Díaz, Obach, Victor, Arenillas, Juan Francisco, Segura, Tomás, Serrano-Heras, Gemma, Martí-Fàbregas, Joan, Freijo, Marimar, Cabezas, Juan Antonio, Tatlisumak, Turgut, Heitsch, Laura, Ibañez, Laura, Cruchaga, Carlos, Lee, Jin-Moo, Strbian, Daniel, Montaner, Joan, Fernández-Cadenas, Israel
Formato: Artigo
Lenguaje:Inglês
Publicado: Lippincott Williams & Wilkins 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6745730/
https://ncbi.nlm.nih.gov/pubmed/31366724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0000000000007997
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