Skeletal muscle MRI differentiates SBMA and ALS and correlates with disease severity

OBJECTIVE: To investigate the use of muscle MRI for the differential diagnosis and as a disease progression biomarker for 2 major forms of motor neuron disorders: spinal bulbar muscular atrophy (SBMA) and amyotrophic lateral sclerosis (ALS). METHODS: We applied quantitative 3-point Dixon and semiqua...

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Detalhes bibliográficos
Publicado no:Neurology
Main Authors: Klickovic, Uros, Zampedri, Luca, Sinclair, Christopher D.J., Wastling, Stephen J., Trimmel, Karin, Howard, Robin S., Malaspina, Andrea, Sharma, Nikhil, Sidle, Katie, Emira, Ahmed, Shah, Sachit, Yousry, Tarek A., Hanna, Michael G., Greensmith, Linda, Morrow, Jasper M., Thornton, John S., Fratta, Pietro
Formato: Artigo
Idioma:Inglês
Publicado em: Lippincott Williams & Wilkins 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6745729/
https://ncbi.nlm.nih.gov/pubmed/31391248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0000000000008009
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