Skeletal muscle MRI differentiates SBMA and ALS and correlates with disease severity

OBJECTIVE: To investigate the use of muscle MRI for the differential diagnosis and as a disease progression biomarker for 2 major forms of motor neuron disorders: spinal bulbar muscular atrophy (SBMA) and amyotrophic lateral sclerosis (ALS). METHODS: We applied quantitative 3-point Dixon and semiqua...

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Détails bibliographiques
Publié dans:Neurology
Auteurs principaux: Klickovic, Uros, Zampedri, Luca, Sinclair, Christopher D.J., Wastling, Stephen J., Trimmel, Karin, Howard, Robin S., Malaspina, Andrea, Sharma, Nikhil, Sidle, Katie, Emira, Ahmed, Shah, Sachit, Yousry, Tarek A., Hanna, Michael G., Greensmith, Linda, Morrow, Jasper M., Thornton, John S., Fratta, Pietro
Format: Artigo
Langue:Inglês
Publié: Lippincott Williams & Wilkins 2019
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6745729/
https://ncbi.nlm.nih.gov/pubmed/31391248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0000000000008009
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