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Bisretinoid Photodegradation Is Likely Not a Good Thing

Retinaldehyde adducts (bisretinoids) accumulate in retinal pigment epithelial (RPE) cells as lipofuscin. Bisretinoids are implicated in some inherited and age-related forms of macular degeneration that lead to the death of RPE cells and diminished vision. By comparing albino and black-eyed mice and...

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Detalhes bibliográficos
Publicado no:Adv Exp Med Biol
Main Authors: Ueda, Keiko, Kim, Hye Jin, Zhao, Jin, Sparrow, Janet R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6745705/
https://ncbi.nlm.nih.gov/pubmed/29721969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-3-319-75402-4_49
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