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Iron promotes oxidative cell death caused by bisretinoids of retina

Intracellular Fe plays a key role in redox active energy and electron transfer. We sought to understand how Fe levels impact the retina, given that retinal pigment epithelial (RPE) cells are also challenged by accumulations of vitamin A aldehyde adducts (bisretinoid lipofuscin) that photogenerate re...

詳細記述

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書誌詳細
出版年:Proc Natl Acad Sci U S A
主要な著者: Ueda, Keiko, Kim, Hye Jin, Zhao, Jin, Song, Ying, Dunaief, Joshua L., Sparrow, Janet R.
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5948992/
https://ncbi.nlm.nih.gov/pubmed/29686088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1722601115
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