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Iron promotes oxidative cell death caused by bisretinoids of retina

Intracellular Fe plays a key role in redox active energy and electron transfer. We sought to understand how Fe levels impact the retina, given that retinal pigment epithelial (RPE) cells are also challenged by accumulations of vitamin A aldehyde adducts (bisretinoid lipofuscin) that photogenerate re...

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Detaylı Bibliyografya
Yayımlandı:Proc Natl Acad Sci U S A
Asıl Yazarlar: Ueda, Keiko, Kim, Hye Jin, Zhao, Jin, Song, Ying, Dunaief, Joshua L., Sparrow, Janet R.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2018
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5948992/
https://ncbi.nlm.nih.gov/pubmed/29686088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1722601115
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