Antiepileptic effects of levetiracetam in a rodent neonatal seizure model

BACKGROUND: Neonatal seizures can result in chronic epilepsy and long-term behavioral and cognitive deficits. Levetiracetam (LEV), an antiepileptic drug that binds to the synaptic vesicle protein 2A (SV2A), has been increasingly used off-label for the therapy of neonatal seizures. Preclinical data r...

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Udgivet i:Pediatr Res
Main Authors: Talos, Delia M., Chang, Meayoung, Kosaras, Bela, Fitzgerald, Erin, Murphy, Andrew, Folkerth, Rebecca Dunn, Jensen, Frances E.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6745697/
https://ncbi.nlm.nih.gov/pubmed/23138400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/pr.2012.151
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