C/EBPα mediates the growth inhibitory effect of progestins on breast cancer cells

Steroid hormones are key gene regulators in breast cancer cells. While estrogens stimulate cell proliferation, progestins activate a single cell cycle followed by proliferation arrest. Here, we use biochemical and genome‐wide approaches to show that progestins achieve this effect via a functional cr...

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Publicat a:EMBO J
Autors principals: Nacht, A Silvina, Ferrari, Roberto, Zaurin, Roser, Scabia, Valentina, Carbonell‐Caballero, José, Le Dily, Francois, Quilez, Javier, Leopoldi, Alexandra, Brisken, Cathrin, Beato, Miguel, Vicent, Guillermo P
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2019
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6745496/
https://ncbi.nlm.nih.gov/pubmed/31373033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2018101426
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