Rectal cancer sub-clones respond differentially to neoadjuvant therapy()

Treatment of locally advanced rectal cancer includes chemotherapy, radiation, and surgery but patient responses to neoadjuvant treatment are variable. We have shown that rectal tumors are comprised of multiple genetically distinct sub-clones. Unique sub-clones within tumors may harbor mutations whic...

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Publicat a:Neoplasia
Autors principals: Frydrych, Lynn M, Ulintz, Peter, Bankhead, Armand, Sifuentes, Christopher, Greenson, Joel, Maguire, Lillias, Irwin, Regina, Fearon, Eric R., Hardiman, Karin M
Format: Artigo
Idioma:Inglês
Publicat: Neoplasia Press 2019
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Original article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6745489/
https://ncbi.nlm.nih.gov/pubmed/31521947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neo.2019.08.004
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