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Conditional deletion of melanin-concentrating hormone receptor 1 from GABAergic neurons increases locomotor activity
OBJECTIVE: Melanin-concentrating hormone (MCH) plays a key role in regulating energy balance. MCH acts via its receptor MCHR1, and MCHR1 deletion increases energy expenditure and locomotor activity, which is associated with a hyperdopaminergic state. Since MCHR1 expression is widespread, the neurons...
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| Udgivet i: | Mol Metab |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Elsevier
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6745487/ https://ncbi.nlm.nih.gov/pubmed/31668382 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2019.08.018 |
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