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Engineering polymerases for new functions

DNA polymerases are critical tools in biotechnology, enabling efficient and accurate amplification of DNA templates, yet many desired functions are not readily available in natural DNA polymerases. New or improved functions can be engineered in DNA polymerases by mutagenesis or through the creation...

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Bibliographic Details
Published in:Trends Biotechnol
Main Authors: Coulther, Timothy A., Stern, Hannah R., Beuning, Penny J.
Format: Artigo
Language:Inglês
Published: 2019
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6745271/
https://ncbi.nlm.nih.gov/pubmed/31003719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tibtech.2019.03.011
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