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Engineering polymerases for new functions

DNA polymerases are critical tools in biotechnology, enabling efficient and accurate amplification of DNA templates, yet many desired functions are not readily available in natural DNA polymerases. New or improved functions can be engineered in DNA polymerases by mutagenesis or through the creation...

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Publicat a:Trends Biotechnol
Autors principals: Coulther, Timothy A., Stern, Hannah R., Beuning, Penny J.
Format: Artigo
Idioma:Inglês
Publicat: 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6745271/
https://ncbi.nlm.nih.gov/pubmed/31003719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tibtech.2019.03.011
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