Identification of multiple male reproductive tract-specific proteins that regulate sperm migration through the oviduct in mice

CRISPR/Cas9-mediated genome editing technology enables researchers to efficiently generate and analyze genetically modified animals. We have taken advantage of this game-changing technology to uncover essential factors for fertility. In this study, we generated knockouts (KOs) of multiple male repro...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Fujihara, Yoshitaka, Noda, Taichi, Kobayashi, Kiyonori, Oji, Asami, Kobayashi, Sumire, Matsumura, Takafumi, Larasati, Tamara, Oura, Seiya, Kojima-Kita, Kanako, Yu, Zhifeng, Matzuk, Martin M., Ikawa, Masahito
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2019
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6744855/
https://ncbi.nlm.nih.gov/pubmed/31455729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1908736116
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