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Activated α(2)-Macroglobulin Regulates LRP1 Levels at the Plasma Membrane through the Activation of a Rab10-dependent Exocytic Pathway in Retinal Müller Glial Cells

Activated α(2)-macroglobulin (α(2)M*) and its receptor, low-density lipoprotein receptor-related protein 1 (LRP1), have been linked to proliferative retinal diseases. In Müller glial cells (MGCs), the α(2)M*/LRP1 interaction induces cell signaling, cell migration, and extracellular matrix remodeling...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Sci Rep
Päätekijät: Jaldín-Fincati, Javier R., Actis Dato, Virginia, Díaz, Nicolás M., Sánchez, María C., Barcelona, Pablo F., Chiabrando, Gustavo A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group UK 2019
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6744500/
https://ncbi.nlm.nih.gov/pubmed/31519919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-49072-6
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