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Activated α(2)-Macroglobulin Regulates LRP1 Levels at the Plasma Membrane through the Activation of a Rab10-dependent Exocytic Pathway in Retinal Müller Glial Cells
Activated α(2)-macroglobulin (α(2)M*) and its receptor, low-density lipoprotein receptor-related protein 1 (LRP1), have been linked to proliferative retinal diseases. In Müller glial cells (MGCs), the α(2)M*/LRP1 interaction induces cell signaling, cell migration, and extracellular matrix remodeling...
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| Publicado no: | Sci Rep |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6744500/ https://ncbi.nlm.nih.gov/pubmed/31519919 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-49072-6 |
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