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Development of R7BP inhibitors through cross-linking coupled mass spectrometry and integrated modeling

Protein-protein interaction (PPI) networks are known to be valuable targets for therapeutic intervention; yet the development of PPI modulators as next-generation drugs to target specific vertices, edges, and hubs has been impeded by the lack of structural information of many of the proteins and com...

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Detalhes bibliográficos
Publicado no:Commun Biol
Main Authors: Adikaram, Poorni R., Zhang, Jian-Hua, Kittock, Claire M., Pandey, Mritunjay, Hassan, Sergio A., Lue, Nicole G., Wang, Guanghui, Gucek, Marjan, Simonds, William F.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6744478/
https://ncbi.nlm.nih.gov/pubmed/31531399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-019-0585-1
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