Cryo-EM structures of lipopolysaccharide transporter LptB(2)FGC in lipopolysaccharide or AMP-PNP-bound states reveal its transport mechanism

Lipopolysaccharides (LPS) of Gram-negative bacteria are critical for the defence against cytotoxic substances and must be transported from the inner membrane (IM) to the outer membrane (OM) through a bridge formed by seven membrane proteins (LptBFGCADE). The IM component LptB(2)FG powers the process...

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Publicado no:Nat Commun
Main Authors: Tang, Xiaodi, Chang, Shenghai, Luo, Qinghua, Zhang, Zhengyu, Qiao, Wen, Xu, Caihuang, Zhang, Changbin, Niu, Yang, Yang, Wenxian, Wang, Ting, Zhang, Zhibo, Zhu, Xiaofeng, Wei, Xiawei, Dong, Changjiang, Zhang, Xing, Dong, Haohao
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6744409/
https://ncbi.nlm.nih.gov/pubmed/31519889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-11977-1
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