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Focal Adhesion Kinase Inhibition Contributes to Tumor Cell Survival and Motility in Neuroblastoma Patient-Derived Xenografts

Patient-derived xenografts (PDXs) provide an opportunity to evaluate the effects of therapies in an environment that more closely resembles the human condition than that seen with long-term passage cell lines. In the current studies, we investigated the effects of FAK inhibition on two neuroblastoma...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Stafman, Laura L., Williams, Adele P., Marayati, Raoud, Aye, Jamie M., Markert, Hooper R., Garner, Evan F., Quinn, Colin H., Lallani, Shoeb B., Stewart, Jerry E., Yoon, Karina J., Whelan, Kimberly, Beierle, Elizabeth A.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6744403/
https://ncbi.nlm.nih.gov/pubmed/31519958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-49853-z
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