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Predicting functional variants in enhancer and promoter elements using RegulomeDB
Here we present a computational model, SURF (Score of Unified Regulatory Features), that predicts functional variants in enhancer and promoter elements. SURF is trained on data from massively parallel reporter assays and predicts the effect of variants on reporter expression levels. It achieved the...
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| Publicado no: | Hum Mutat |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6744346/ https://ncbi.nlm.nih.gov/pubmed/31228310 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/humu.23791 |
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