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Predicting functional variants in enhancer and promoter elements using RegulomeDB
Here we present a computational model, SURF (Score of Unified Regulatory Features), that predicts functional variants in enhancer and promoter elements. SURF is trained on data from massively parallel reporter assays and predicts the effect of variants on reporter expression levels. It achieved the...
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| Udgivet i: | Hum Mutat |
|---|---|
| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6744346/ https://ncbi.nlm.nih.gov/pubmed/31228310 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/humu.23791 |
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