Vaccine-Mediated Inhibition of the Transporter Associated with Antigen Processing Is Insufficient To Induce Major Histocompatibility Complex E-Restricted CD8(+) T Cells in Nonhuman Primates

Major histocompatibility complex E (MHC-E) is a highly conserved nonclassical MHC-Ib molecule that tightly binds peptides derived from leader sequences of classical MHC-Ia molecules for presentation to natural killer cells. However, MHC-E also binds diverse foreign and neoplastic self-peptide antige...

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Detalles Bibliográficos
Publicado en:J Virol
Main Authors: Abdulhaqq, Shaheed A., Wu, Helen, Schell, John B., Hammond, Katherine B., Reed, Jason S., Legasse, Alfred W., Axthelm, Michael K., Park, Byung S., Asokan, Aravind, Früh, Klaus, Hansen, Scott G., Picker, Louis J., Sacha, Jonah B.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2019
Assuntos:
Vaccines and Antiviral Agents
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6744250/
https://ncbi.nlm.nih.gov/pubmed/31315990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00592-19
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