IL-15 induces CD4(+) effector memory T cell production and tissue emigration in nonhuman primates

HIV infection selectively targets CD4(+) effector memory T (T(EM)) cells, resulting in dramatic depletion of CD4(+) T cells in mucosal effector sites in early infection. Regeneration of the T(EM) cell compartment is slow and incomplete, even when viral replication is controlled by antiretroviral the...

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Detalhes bibliográficos
Main Authors: Picker, Louis J., Reed-Inderbitzin, Edward F., Hagen, Shoko I., Edgar, John B., Hansen, Scott G., Legasse, Alfred, Planer, Shannon, Piatak, Michael, Lifson, Jeffrey D., Maino, Vernon C., Axthelm, Michael K., Villinger, Francois
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2006
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1459071/
https://ncbi.nlm.nih.gov/pubmed/16691294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI27564
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