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Deconvolving multiplexed protease signatures with substrate reduction and activity clustering
Proteases are multifunctional, promiscuous enzymes that degrade proteins as well as peptides and drive important processes in health and disease. Current technology has enabled the construction of libraries of peptide substrates that detect protease activity, which provides valuable biological infor...
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| Publicat a: | PLoS Comput Biol |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Public Library of Science
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6743790/ https://ncbi.nlm.nih.gov/pubmed/31479443 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1006909 |
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