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Benchmarking network propagation methods for disease gene identification

In-silico identification of potential target genes for disease is an essential aspect of drug target discovery. Recent studies suggest that successful targets can be found through by leveraging genetic, genomic and protein interaction information. Here, we systematically tested the ability of 12 var...

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Dettagli Bibliografici
Pubblicato in:PLoS Comput Biol
Autori principali: Picart-Armada, Sergio, Barrett, Steven J., Willé, David R., Perera-Lluna, Alexandre, Gutteridge, Alex, Dessailly, Benoit H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6743778/
https://ncbi.nlm.nih.gov/pubmed/31479437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1007276
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