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Benchmarking network propagation methods for disease gene identification

In-silico identification of potential target genes for disease is an essential aspect of drug target discovery. Recent studies suggest that successful targets can be found through by leveraging genetic, genomic and protein interaction information. Here, we systematically tested the ability of 12 var...

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Detalhes bibliográficos
Publicado no:PLoS Comput Biol
Main Authors: Picart-Armada, Sergio, Barrett, Steven J., Willé, David R., Perera-Lluna, Alexandre, Gutteridge, Alex, Dessailly, Benoit H.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6743778/
https://ncbi.nlm.nih.gov/pubmed/31479437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1007276
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