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Hepatic metabolic adaptation in a murine model of glutathione deficiency

Glutathione (GSH), the most abundant cellular non-protein thiol, plays a pivotal role in hepatic defense mechanisms against oxidative damage. Despite a strong association between disrupted GSH homeostasis and liver diseases of various etiologies, it was shown that GSH-deficient glutamate-cysteine li...

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Detalhes bibliográficos
Publicado no:Chem Biol Interact
Main Authors: Chen, Ying, Golla, Srujana, Garcia-Milian, Rolando, Thompson, David C., Gonzalez, Frank J., Vasiliou, Vasilis
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6743730/
https://ncbi.nlm.nih.gov/pubmed/30794799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbi.2019.02.015
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