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Total Synthesis and Anti-Cancer Activity of All Known Communesin Alkaloids and Related Derivatives

[Image: see text] A unified enantioselective total synthesis and anticancer evaluation of all known epoxide-containing communesin alkaloids and related derivatives is described. Our synthesis is predicated on the convergent and modular diazene-directed assembly of two complex fragments to secure the...

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Библиографические подробности
Опубликовано в: :J Am Chem Soc
Главные авторы: Pompeo, Matthew M., Cheah, Jaime H., Movassaghi, Mohammad
Формат: Artigo
Язык:Inglês
Опубликовано: American Chemical Society 2019
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6743222/
https://ncbi.nlm.nih.gov/pubmed/31422662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.9b07397
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