SCP2-mediated cholesterol membrane trafficking promotes the growth of pituitary adenomas via Hedgehog signaling activation

BACKGROUND: Metabolic reprogramming is an important characteristic of tumors. In the progression of pituitary adenomas (PA), abnormal glucose metabolism has been confirmed by us before. However, whether cholesterol metabolism is involved in the process of PA remains unclear. This study aimed to inve...

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Detalhes bibliográficos
Publicado no:J Exp Clin Cancer Res
Main Authors: Ding, Xiao, Fan, Kexia, Hu, Jintao, Zang, Zhenle, Zhang, Shunli, Zhang, Yin, Lin, Zhichao, Pei, Xiangdong, Zheng, Xin, Zhu, Feng, Yang, Hui, Li, Song
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6743201/
https://ncbi.nlm.nih.gov/pubmed/31519191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-019-1411-9
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