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Maximizing Longevity and Healthspan: Multiple Approaches All Converging on Autophagy

Our understanding of the molecular basis of aging has greatly increased over the past few decades. In this review, we provide an overview of the key signaling pathways associated with aging, and whose modulation has been shown to extend lifespan in a range of model organisms. We also describe how th...

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Detalhes bibliográficos
Publicado no:Front Cell Dev Biol
Main Authors: Bareja, Akshay, Lee, David E., White, James P.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6742954/
https://ncbi.nlm.nih.gov/pubmed/31555646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2019.00183
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