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Maximizing Longevity and Healthspan: Multiple Approaches All Converging on Autophagy

Our understanding of the molecular basis of aging has greatly increased over the past few decades. In this review, we provide an overview of the key signaling pathways associated with aging, and whose modulation has been shown to extend lifespan in a range of model organisms. We also describe how th...

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Pubblicato in:Front Cell Dev Biol
Autori principali: Bareja, Akshay, Lee, David E., White, James P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6742954/
https://ncbi.nlm.nih.gov/pubmed/31555646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2019.00183
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