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Influence of Rifampin‐Mediated Organic Anion‐Transporting Polypeptide 1B1/1B3 Inhibition on the Pharmacokinetics of Clazosentan
Clazosentan is a selective endothelin A receptor antagonist in development for the prevention and treatment of vasospasm postsubarachnoid hemorrhage. It is a substrate of organic anion‐transporting polypeptide 1B1/1B3 based on preclinical data. This randomized, double‐blind, two‐period, cross‐over s...
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| Yayımlandı: | Clin Transl Sci |
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| Asıl Yazarlar: | , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
John Wiley and Sons Inc.
2019
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6742933/ https://ncbi.nlm.nih.gov/pubmed/31004470 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cts.12639 |
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