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Genetic reprogramming for NK cell cancer immunotherapy with CRISPR/Cas9
Natural killer cells are potent cytotoxic lymphocytes specialized in recognizing and eliminating transformed cells, and in orchestrating adaptive anti‐tumour immunity. However, NK cells are usually functionally exhausted in the tumour microenvironment. Strategies such as checkpoint blockades are und...
Shranjeno v:
| izdano v: | Immunology |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
John Wiley and Sons Inc.
2019
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6742769/ https://ncbi.nlm.nih.gov/pubmed/31315144 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.13094 |
| Oznake: |
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