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Cell Type-Specific Roles for Tissue Plasminogen Activator Released by Neurons or Microglia after Excitotoxic Injury

Tissue plasminogen activator (tPA) plays important roles in the brain after excitotoxic injury. It is released by both neurons and microglia and mediates neuronal death and microglial activation. Mice lacking tPA are resistant to excitotoxicity and show very limited microglial activation. Activated...

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Vydáno v:J Neurosci
Hlavní autoři: Siao, Chia-Jen, Fernandez, Susana R., Tsirka, Stella E.
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2003
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6742309/
https://ncbi.nlm.nih.gov/pubmed/12716930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.23-08-03234.2003
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