The H(+)-Coupled Electrogenic Lysosomal Amino Acid Transporter LYAAT1 Localizes to the Axon and Plasma Membrane of Hippocampal Neurons

Recent work has identified a lysosomal protein that transports neutral amino acids (LYAAT1). We now show that LYAAT1 mediates H(+) cotransport with a stoichiometry of 1 H(+)/1 amino acid, consistent with a role in the active efflux of amino acids from lysosomes. In neurons, however, LYAAT1 localizes...

Full description

Saved in:
Bibliographic Details
Published in:J Neurosci
Main Authors: Wreden, Christopher C., Johnson, Juliette, Tran, Cindy, Seal, Rebecca P., Copenhagen, David R., Reimer, Richard J., Edwards, Robert H.
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 2003
Subjects:
ARTICLE
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6742289/
https://ncbi.nlm.nih.gov/pubmed/12598615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.23-04-01265.2003
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items