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The Wld(s) Mutation Delays Robust Loss of Motor and Sensory Axons in a Genetic Model for Myelin-Related Axonopathy

Mice deficient in the peripheral myelin component P0 mimic severe forms of inherited peripheral neuropathies in humans, with defective myelin formation and consequent axonal loss. We cross-bred these mice with the spontaneous mutant C57BL/Wld(s)typically showing protection from Wallerian degeneratio...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Samsam, Mohtashem, Mi, Weiqian, Wessig, Carsten, Zielasek, Jürgen, Toyka, Klaus V., Coleman, Michael P., Martini, Rudolf
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6742108/
https://ncbi.nlm.nih.gov/pubmed/12684470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.23-07-02833.2003
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