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Inhibition of Bax-Induced Cytochrome c Release from Neural Cell and Brain Mitochondria by Dibucaine and Propranolol

BH3 (Bcl-2 homology 3)-only proteins of the Bcl-2 family activate Bax or Bak during apoptosis to promote the release of pro-death factors sequestered in the mitochondrial intermembrane space. Previous results demonstrated that a synthetic BH3 peptide mimics the ability of the BH3-only protein Bid to...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Polster, Brian M., Basañez, Gorka, Young, Michael, Suzuki, Motoshi, Fiskum, Gary
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6742107/
https://ncbi.nlm.nih.gov/pubmed/12684459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.23-07-02735.2003
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