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A Chondroitin Sulfate Proteoglycan PTPζ/RPTPβ Regulates the Morphogenesis of Purkinje Cell Dendrites in the Developing Cerebellum

PTPζ/RPTPβ, a receptor-type protein tyrosine phosphatase synthesized as a chondroitin sulfate (CS) proteoglycan, uses a heparin-binding growth factor pleiotrophin (PTN) as a ligand, in which the CS portion plays an essential role in ligand binding. Using an organotypic slice culture system, we teste...

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Detalles Bibliográficos
Publicado en:J Neurosci
Main Authors: Tanaka, Masahiko, Maeda, Nobuaki, Noda, Masaharu, Marunouchi, Tohru
Formato: Artigo
Idioma:Inglês
Publicado: Society for Neuroscience 2003
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6742081/
https://ncbi.nlm.nih.gov/pubmed/12684467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.23-07-02804.2003
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