Proteolipid Protein Gene Mutation Induces Altered Ventilatory Response to Hypoxia in the Myelin-Deficient Rat

Pelizaeus Merzbacher disease is an X-linked dysmyelinating disorder of the CNS, resulting from mutations in the proteolipid protein (PLP) gene. An animal model for this disorder, the myelin-deficient (MD) rat, carries a point mutation in thePLP gene and exhibits a phenotype similar to the fatal, con...

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發表在:J Neurosci
Main Authors: Miller, Martha J., Haxhiu, Musa A., Georgiadis, Paraskevi, Gudz, Tatyana I., Kangas, Cindy D., Macklin, Wendy B.
格式: Artigo
語言:Inglês
出版: Society for Neuroscience 2003
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ARTICLE
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6742015/
https://ncbi.nlm.nih.gov/pubmed/12657685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.23-06-02265.2003
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