Aberrant Patterning of Neuromuscular Synapses in Choline Acetyltransferase-Deficient Mice

In this study we examined the developmental roles of acetylcholine (ACh) by establishing and analyzing mice lacking choline acetyltransferase (ChAT), the biosynthetic enzyme for ACh. As predicted, ChAT-deficient embryos lack both spontaneous and nerve-evoked postsynaptic potentials in muscle and die...

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Pubblicato in:J Neurosci
Autori principali: Brandon, Eugene P., Lin, Weichun, D'Amour, Kevin A., Pizzo, Donald P., Dominguez, Bertha, Sugiura, Yoshie, Thode, Silke, Ko, Chien-Ping, Thal, Leon J., Gage, Fred H., Lee, Kuo-Fen
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2003
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6741871/
https://ncbi.nlm.nih.gov/pubmed/12533614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.23-02-00539.2003
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