Construction and characterization of a truncated tissue factor-coagulation-based composite system for selective thrombosis in tumor blood vessels

The selective induction of tumor vascular thrombosis using truncated tissue factor (tTF) delivered via a target ligand is a promising novel antitumor strategy. In the present study, an anti-neuropilin-1 (NRP-1) monoclonal antibody (mAb)-streptavidin (SA):tTF-biotin (B) composite system was establish...

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Publicado no:Int J Oncol
Main Authors: Xu, Peilan, Zou, Mingyuan, Wang, Shengyu, Li, Tingting, Liu, Cong, Wang, Li, Wang, Lanlan, Luo, Fanghong, Wu, Ting, Yan, Jianghua
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2019
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6741845/
https://ncbi.nlm.nih.gov/pubmed/31432158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijo.2019.4855
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