Clinical Exome Sequencing vs. Usual Care for Hereditary Colorectal Cancer Diagnosis: A Pilot Comparative Effectiveness Study

BACKGROUND: Clinical exome sequencing (CES) provides the advantage of assessing genetic variation across the human exome compared to a traditional stepwise diagnostic approach or multi-gene panels. Comparative effectiveness research methods offer an approach to better understand the patient-centered...

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Veröffentlicht in:Contemp Clin Trials
Hauptverfasser: Niu, Xin, Amendola, Laura M., Hart, Ragan, Bennette, Caroline S., Heagerty, Patrick, Horike-Pyne, Martha, Trinidad, Susan B., Rosenthal, Elisabeth A., Comstock, Bryan, Nefcy, Chris, Hisama, Fuki M, Bennett, Robin L., Grady, William M., Gallego, Carlos J., Tarczy-Hornoch, Peter, Fullerton, Stephanie M, Burke, Wylie, Regier, Dean A., Dorschner, Michael O., Shirts, Brian H., Robertson, Peggy D., Nickerson, Deborah A., Patrick, Donald L., Jarvik, Gail P., Veenstra, David L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6741782/
https://ncbi.nlm.nih.gov/pubmed/31400517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cct.2019.105820
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