Blood Outgrowth Endothelial Cells overexpressing eNOS mitigate pulmonary hypertension in rats: A unique carrier cell enabling autologous cell-based gene therapy

We have investigated a unique cell type, Blood Outgrowth Endothelial Cells (BOEC), as a cell-based gene therapy approach to pulmonary hypertension. BOEC are bona fide endothelial cells, obtained from peripheral blood, that can be expanded to vast numbers, and are amenable to both cryopreservation an...

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Detalhes bibliográficos
Publicado no:Transl Res
Main Authors: Somani, Arif, Nair, Sethu L, Milbauer, Liming C, Zhu, Guangshuo, Sajja, Suchitra, Solovey, Anna, Chen, Yingjie, Hebbel, Robert P
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6741773/
https://ncbi.nlm.nih.gov/pubmed/31082372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.trsl.2019.04.005
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