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Pharmacological Properties, Central Nervous System Effects, and Potential Therapeutic Applications of Atipamezole, a Selective α(2)‐Adrenoceptor Antagonist

Atipamezole is an α(2)‐adrenoceptor antagonist with an imidazole structure. Receptor binding studies indicate that its affinity for α(2)‐adrenoceptors and its α(2)/α(1) selectivity ratio are considerably higher than those of yohimbine, the prototype α(2)‐adrenoceptor antagonist. Atipamezole is not s...

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Detalhes bibliográficos
Publicado no:CNS Drug Rev
Main Authors: Pertovaara, Antti, Haapalinna, Antti, Sirviö, Jouni, Virtanen, Raimo
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6741735/
https://ncbi.nlm.nih.gov/pubmed/16389294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1527-3458.2005.tb00047.x
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