In vitro α(1)-adrenoceptor pharmacology of Ro 70-0004 and RS-100329, novel α(1A)-adrenoceptor selective antagonists

1. It has been hypothesized that in patients with benign prostatic hyperplasia, selective antagonism of the α(1A)-adrenoceptor-mediated contraction of lower urinary tract tissues may, via a selective relief of outlet obstruction, lead to an improvement in symptoms. 2. The present study describes the...

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Autors principals: Williams, T J, Blue, D R, Daniels, D V, Davis, B, Elworthy, T, Gever, J R, Kava, M S, Morgans, D, Padilla, F, Tassa, S, Vimont, R L, Chapple, C R, Chess-Williams, R, Eglen, R M, Clarke, D E, Ford, A P D W
Format: Artigo
Idioma:Inglês
Publicat: 1999
Matèries:
Papers
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1566006/
https://ncbi.nlm.nih.gov/pubmed/10369480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702541
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