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The Selective Serotonin Reuptake Inhibitor Sertraline: Its Profile and Use in Psychiatric Disorders
ABSTRACT: The naphthylamine derivative sertraline is a potent and selective inhibitor of serotonin reuptake into presynaptic terminals. Sertraline has a linear pharmacokinetic profile and a half‐life of about 26 h. Its major metabolite, desmethylsertraline does not appear to inhibit serotonin reupta...
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| Publié dans: | CNS Drug Rev |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Blackwell Publishing Ltd
2006
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6741657/ https://ncbi.nlm.nih.gov/pubmed/11420570 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1527-3458.2001.tb00188.x |
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