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The Selective Serotonin Reuptake Inhibitor Sertraline: Its Profile and Use in Psychiatric Disorders

ABSTRACT: The naphthylamine derivative sertraline is a potent and selective inhibitor of serotonin reuptake into presynaptic terminals. Sertraline has a linear pharmacokinetic profile and a half‐life of about 26 h. Its major metabolite, desmethylsertraline does not appear to inhibit serotonin reupta...

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Detalhes bibliográficos
Publicado no:CNS Drug Rev
Main Authors: MacQueen, Glenda, Born, Leslie, Steiner, Meir
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6741657/
https://ncbi.nlm.nih.gov/pubmed/11420570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1527-3458.2001.tb00188.x
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