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Donepezil for Alzheimer's Disease: Pharmacodynamic, Pharmacokinetic, and Clinical Profiles

Donepezil was developed in order to overcome the disadvantages of physostigmine and tacrine. Its use is based on the cholinergic hypothesis. Donepezil is a piperidine‐based, reversible acetylcholinesterase inhibitor, that is chemically unrelated to other cholinesterase inhibitors. It was developed f...

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Bibliografske podrobnosti
izdano v:CNS Drug Rev
Main Authors: Shigeta, Masahiro, Homma, Akira
Format: Artigo
Jezik:Inglês
Izdano: Blackwell Publishing Ltd 2006
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6741644/
https://ncbi.nlm.nih.gov/pubmed/11830754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1527-3458.2001.tb00204.x
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