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Processing of Laminin α Chains Generates Peptides Involved in Wound Healing and Host Defense

Laminins play a fundamental role in basement membrane architecture and function in human skin. The C-terminal laminin G domain-like (LG) modules of laminin α chains are modified by proteolysis to generate LG1-3 and secreted LG4-5 tandem modules. In this study, we provide evidence that skin-derived c...

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Detalhes bibliográficos
Publicado no:J Innate Immun
Main Authors: Senyürek, Ilknur, Kempf, Wolfgang E., Klein, Gerd, Maurer, Andreas, Kalbacher, Hubert, Schäfer, Luisa, Wanke, Ines, Christ, Christina, Stevanovic, Stefan, Schaller, Martin, Rousselle, Patricia, Garbe, Claus, Biedermann, Tilo, Schittek, Birgit
Formato: Artigo
Idioma:Inglês
Publicado em: S. Karger AG 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6741626/
https://ncbi.nlm.nih.gov/pubmed/24458132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000357032
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