The Antimicrobial Peptide LL-37 Alters Human Osteoblast Ca(2+) Handling and Induces Ca(2+)-Independent Apoptosis

The human antimicrobial peptide cathelicidin LL-37 has, besides its antimicrobial properties, also been shown to regulate apoptosis in a cell type-specific manner. Mechanisms involved in LL-37-regulated apoptotic signaling are not identified. Here, we show that LL-37 reduces the human osteoblast-lik...

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Detalhes bibliográficos
Publicado no:J Innate Immun
Main Authors: Säll, Johanna, Carlsson, Martin, Gidlöf, Olof, Holm, Anders, Humlén, Johan, Öhman, Jenny, Svensson, Daniel, Nilsson, Bengt-Olof, Jönsson, Daniel
Formato: Artigo
Idioma:Inglês
Publicado em: S. Karger AG 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6741588/
https://ncbi.nlm.nih.gov/pubmed/23406612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000346587
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